49ers vs Raiders Prediction, Picks & Odds for This Week’s NFL Preseason Game

It’s official, Gardner Minshew is the Las Vegas Raiders’ starting quarterback, but he won’t be taking the field against the San Francisco 49ers. Will that deter our 49ers vs. Raiders predictions from backing the hosts?

Find out why my NFL picks are siding with Las Vegas on Friday, August 23.  

49ers vs Raiders prediction

My best betRaiders +7.5 (-110 at bet365)

My analysis

Nobody is overly confident in a QB combo of Carter Bradley and Nathan Peterman, however, the San Francisco 49ers aren’t expected to play any of their key players either.

Winning by more than 7.5 points in a battle of backup players fighting to make the 53-man roster is a tall task, even for the defending …